Manske Lab

Projects

Explore what our lab is currently working on!

Please note some repositories are still private but might be made public in the future.

Assessing Carpal Alignment and Kinematics Using WBCT

Assessing Carpal Alignment and Kinematics Using WBCT

Utilizing weight-bearing computed tomography (WBCT) to evaluate carpal biomechanics.

CBCT Image Super-Resolution

CBCT Image Super-Resolution

Developement and validation of a deep learning model to enhance image resolution and quality of cone-beam computed tomography (CBCT) images of the metacarpophalangeal joints (knuckles of the hand).

Investigating The Relationship Between Bone and Joint Parameters in Knee Osteoarthritis

Investigating The Relationship Between Bone and Joint Parameters in Knee Osteoarthritis

Using weight-bearing CT and advanced imaging, this research maps 3D joint changes in knee osteoarthritis, leveraging shape modeling and analysis to explore bone geometry’s impact on joint loading and health.

Muscle Loss and Weakness in Critical Care

Muscle Loss and Weakness in Critical Care

An interdisciplinary approach to investigate the time course and nature of muscle weakness during and after a critical care stay.

Characterization of Bone Marrow Lesions in Human Knee Osteoarthritis

Characterization of Bone Marrow Lesions in Human Knee Osteoarthritis

Using an end stage OA human knee model to characterize the bone morphology and remodeling rates of BMLs as well as the types of cells associated using advanced imaging, tetracycline histology, and spatial transcriptomics.

Atlas of Articular Cartilage

Atlas of Articular Cartilage

Structural and functional comparison across species

CBCT Healthy Hand Atlas

CBCT Healthy Hand Atlas

Imaging atlas developed from healthy cone beam CT images.